2025:
Taylor SA, Bader GD, MacParland S, Mullen AC, Andrews T, Cuenca AG, DasGupta R, Gehring AJ, Grün D, Guilliams M, Gulamhusein A, Henderson NC, Hirschfield G, Huppert SS, Itzkovitz S, Jiang ZG, Lauer GM, McGilvray I, Mysore KR, Pirola CJ, Quon G, Rahbari M, Regev A, Ricciuto A, Scott CL, Sharma A, Sookoian S, Tana MM, Teichmann SA, Vallier L, Vlachos IS, Wang B, Zhen M. (2025) Towards a reference cell atlas of liver diversity over the human lifespan. Nat Rev Gastroenterol Hepatol. 2025 Oct 13. PMID: 41083606.
Tabula Microcebus Consortium, Ezran C, Liu S, Chang S, Ming J, Botvinnik O, Penland L, Tarashansky A, de Morree A, Travaglini KJ, Zhao J, Wang G, Hasegawa K, Sin H, Sit R, Okamoto J, Sinha R, Zhang Y, Karanewsky CJ, Pendleton JL, Morri M, Perret M, Aujard F, Stryer L, Artandi S, Fuller MT, Weissman IL, Rando TA, Ferrell JE, Wang B, De Vlaminck I, Yang C, Casey KM, Albertelli MA, Pisco AO, Karkanias J, Neff N, Wu AR, Quake SR, Krasnow MA. (2025) A molecular cell atlas of mouse lemur, an emerging model primate. Nature. 2025 Aug; 644(8075):173-184. PMID: 40739356; PMCID: PMC12328211.
Ezran C, Liu S, Chang S, Ming J, Guethlein LA, Wang MFZ, Dehghannasiri R, Olivieri J, Frank HK, Tarashansky A, Koh W, Jing Q, Botvinnik O, Antony J, Tabula Microcebus Consortium, Pisco AO, Karkanias J, Yang C, Ferrell JE, Boyd SD, Parham P, Long JZ, Wang B, Salzman J, De Vlaminck I, Wu AR, Quake SR, Krasnow MA. (2025) Mouse lemur cell atlas informs primate genes, physiology and disease. Nature. 2025 Aug; 644(8075):185-196. PMID: 40739355; PMCID: PMC12328237.
Merati M, Jayakumar N, Kapoor Y, Naik H, Balwani M, Anderson KE, Bonkovsky HL, Desnick RJ, McGuire B, Phillips J, Bissell DM, Wang B. (2025) A Prospective, Blinded Study of Symptom Prevalence and Specificity of Porphyrin Precursors in Carriers of Acute Hepatic Porphyria. Liver Int. 2025 Jul; 45(7):e70156. PMID: 40485347; PMCID: PMC12146827.
Rademaker G, Hernandez GA, Seo Y, Dahal S, Miller-Phillips L, Li AL, Peng XL, Luan C, Qiu L, Liegeois MA, Wang B, Wen KW, Kim GE, Collisson EA, Kruger SF, Boeck S, Ormanns S, Guenther M, Heinemann V, Haas M, Looney MR, Yeh JJ, Zoncu R, Perera RM. (2025) PCSK9 drives sterol-dependent metastatic organ choice in pancreatic cancer. Nature. 2025 Jul; 643(8074):1381-1390. PMID: 40399683.
Lissing M, Wang B, Wahlin S. (2025) Liver transplantation and primary liver cancer in porphyria. Liver International. 2025 Mar; 45(3):e15894. PMCID: PMC11815609.
Levy C, Naik H, Overbey J, Hedstrom K, Wang K, McDonough C, Freeman M, Keel SB, Erwin AL, Dickey AK, Leaf RK, Quigley J, Mazepa M, Wang B, Phillips J, Parker C, McGuire B, Kazamel M, Bonkovsky H, Rudnick S, Anderson KE, Moghe A, Thapar M, Saberi B, Wheeden K, Desnick R, Balwani M, Porphyrias Consortium of the Rare Diseases Clinical Research Network. (2025) Liver involvement in a large cohort of patients with erythropoietic protoporphyria or X-linked protoporphyria. Hepatol Commun. 2025 Mar 01; 9(3). PMID: 39969427; PMCID: PMC11841850.
Kim JJ, Kurial SNT, Choksi PK, Nunez M, Lunow-Luke T, Bartel J, Driscoll J, Her CL, Dhillon S, Yue W, Murti A, Mao T, Ramos JN, Tiyaboonchai A, Grompe M, Mattis AN, Syed SM, Wang BM, Maher JJ, Roll GR, Willenbring H. (2025) AAV capsid prioritization in normal and steatotic human livers maintained by machine perfusion. Nat Biotechnol. 2025 Jan 29. PMID: 39881029. PMCID: PMC12304247.
Bhasuran B, Schmolly K, Kapoor Y, Jayakumar NL, Doan R, Amin J, Meninger S, Cheng N, Deering R, Anderson K, Beaven SW, Rudrapatna VA, Wang B. (2025) Reducing diagnostic delays in Acute Hepatic Porphyria using electronic health records data and machine learning: a multicenter development and validation study. J Am Med Inform Assoc. 2025 Jan 01; 32(1):63-70. PMID: 38946554. PMCID: PMC11648717.
2024:
Sardh E, Balwani M, Rees DC, Anderson KE, Jia G, Sweetser MT, Wang B. (2024) Long-term follow-up of givosiran treatment in patients with acute intermittent porphyria from a phase 1/2, 48-month open-label extension study. Orphanet J Rare Dis. 2024 Oct 03; 19(1):365. PMID: 39363243; PMCID: PMC11448181.
Alkhani A, Baskaran S, Murti A, Rapp B, Levy CS, Wang B, Nijagal A. (2024) Perinatal liver inflammation is associated with persistent elevation of CXCL10 and its canonical receptor CXCR3 on common myeloid progenitors. bioRxiv. 2024 Aug 19. PMCID: PMC11370417.
Liu S, Ezran C, Wang MFZ, Li Z, Awayan K, Tabula Microcebus Consortium, Long JZ, De Vlaminck I, Wang S, Epelbaum J, Kuo CS, Terrien J, Krasnow MA, Ferrell JE. (2024) An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome. Nat Commun. 2024 Mar 11; 15(1):2188. PMCID: PMC10928088.
2023:
The COVID Tissue Atlas Consortium, Granados AA, Bucher S, Agrawal A, Song H, Chen AT, Peng T, Neff N, Pisco AO, Huang F, Wang, B. (2023) Single-nuclei characterizatino of pervasive transcriptional signatures across organs in response ot COVID-19. eLife. 2023 10 13; 12. PMID: 37830426. PMCID: PMC10575628.
Levy C, Dickey AK, Wang B, Thapar M, Naik H, Keel SB, Saberi B, Beaven SW, Rudnick SR, Elmariah SB, Erwin AL, Goddu RJ, Hedstrom K, Leaf RK, Kazamel M, Mazepa M, Philpotts LL, Quigley J, Raef H, Ungar J, Anderson KE, Balwani M. (2023) Evidence based consensus guidelines for diagnosis and management of Protoporphyria-Related liver dysfunction in erythropoietic protoporphyria and X-Linked protoporphyria. Hepatology. 2023 Jul 27. PMID: 37505211. PMCID: PMC10818013.
Wang B, Bonkovsky HL, Lim JK, Balwani M. (2023) AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review. Gastroenterology. 2023 03; 164(3):484-491. PMID: 36642627; PMCID: PMC10335308.
Liu J, Tran V, Vemuri VNP, Byrne A, Borja M, Kim YJ, Agarwal S, Wang R, Awayan K, Murti A, Taychameekiatchai A, Wang B, Emanuel G, He J, Haliburton J, Oliveira Pisco A, Neff NF. (2023) Concordance of MERFISH spatial transcriptomics with bulk and single-cell RNA sequencing. Life Sci Alliance. 2023 01; 6(1). PMID: 36526371; PMCID: PMC9760489.
2022:
Song H, Bucher S, Rosenberg K, Tsui M, Burhan D, Hoffman D, Cho SJ, Rangaswami A, Breese M, Leung S, Ventura MVP, Sweet-Cordero EA, Huang FW, Nijagal A, Wang B. (2022) Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids. Nat Commun. 2022 08 25; 13(1):4878. PMID: 36008377
Tabula Sapiens Consortium (2022) The Tabula Sapiens: a single cell transcriptomic atlas of multiple organs from individual human donors. Science, 376(6594). PMID: 35549404
Zhang MJ, Hou K, Dey KK, Jagadeesh KA, Weinand K, Sakaue S, Taychameekiatchai A, Rao P, Pisco AO, Zou J, Wang B, Gandal M, Raychaudhuri S, Pasaniuc B, Price AL. (2022) Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data. Nature Genetics 54:1572-1580. PMID: 36050550
Pálovics, R., Keller, A., Schaum, N., Tan, W., Fehlmann, T., Tabula Muris Consortium, & Wyss-Coray, T. (2022). Molecular hallmarks of heterochronic parabiosis at single-cell resolution. Nature, 603:309-314. PMID: 35236985.
Song H, Weinstein HNW, Allegakoen P, Wadsworth MH, Xie J, Yang H, Feng FY, Carroll PR, Wang B, Cooperberg MR, Shalek AK, Huang FW. (2022) Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states. Nature Communications 13:141.
2021:
Kathiriya JJ, Wang C, Zhou M, Brumwell A, Cassandras M, Le Saux C, Cohen M, Alysandratos KD, Wang B, Wolters P, Matthay M, Kotton DN, Chapman HA, Peng T. (2021) Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells. Nature Cell Biology 24:10-23. PMID 34969962.
Liu S, Ezran C, Wang MFZ, Li Z, Tabula Microcebus Consortium, Long JZ, DeVlaminck I, Wang S, Kuo C, Epelbaum J, Terrien J, Krasnow MA, Ferrell JE. An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome. bioRxiv, December 132021.12.13.472243.
Tabula Microcebus Consortium, Ezran C, Liu S, Chang S, Ming J, Botvinnik O, Penland L, Tarashansky A, de Morree A, Travaglini KJ, Hasegawa K, Sin H, Sit R, Okamoto J, Sinha R, Zhang Y, Karanewsky CJ, Pendleton JL, Morri M, Perret M, Aujard F, Stryer L, Artandi S, Fuller M, Weissman, IL, Rando TA, Ferrell JE, Wang B, De Vlaminck I, Yan C, Casey KM, Albertelli MA, Pisco AO, Karkanias J, Neff N, Wu A, Quake SR, Krasnow MA. (2021) Tabula Microcebus: a transcriptomic cell atlas of mouse lemur, an emerging primate model organism. BioRxiv. December 12. https://doi.org/10.1101/2021.12.12.469460.
Olivieri JE, Dehghannasiri R, Wang PL, Jang SR, Morree A, Tan SY, Ming J, Wu AR, Tabula Sapiens Consortium, Quake SR, Krasnow MA, Salzman J. RNA splicing programs define tissue compartments and cell types at single-cell resolution. eLife. 2021;10:e70692. Doi: 10.7554/eLife.70692. PMCID: PMC8563012
Liang B, Zhou Y, Qian M, Xu M, Wang J, Zhang Y, Song X, Wang H, Lin S, Ren C, Monga SP, Wang B, Evert M, Chen Y, Chen X, Huang Z, Calvisi DF, Chen X. (2021) TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis. J Hepatol. PMID: 33577921.
Russell JP, Lim X, Santambrogio A, Yianni V, Kemkem Y, Wang B, Fish M, Haston S, Grabek A, Hallang S, Lodge EJ, Patist AL, Schedl A, Mollard P, Nusse R, Andoniadou CL. Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells. Elife. 2021 Jan 5;10. PMID: 33399538.
Dickey AK, Quick C, Ducamp S, Zhu Z, Feng YA, Naik H, Balwani M, Anderson KE, Lin X, Phillips JE, Rebeiz L, Bonkovsky HL, McGuire BM, Wang B, Chasman DI, Smoller JW, Fleming MD, Christiani DC. Evidence in the UK Biobank for the underdiagnosis of erythropoietic protoporphyria. Genet Med. 2021 Jan;23(1):140-148. PMID: 32873934.
2020:
The Tabula Muris Consortium (2020) A single cell transcriptomic atlas characterizes aging tissues in the mouse. Nature 583:590-595. (PDF)
Schaum N., Lehallier B., Hahn O., Palovics R., Hosseinzadeh S., Lee S.E., Sit R., Lee D.P., Losada P.M., Zardenata M.E., Fehlmann T., Webber J., McGeever A., Calcuttawala K., Zhang H., Berdnik D., Mathur V., Tan W., Zee A., Tan M., The Tabula Muris Consortium, Pisco A., Karnanias J., Neff N.F., Keller A., Darmanis S., Quake S.R., Wyss-Coray T. (2020) Ageing hallmarks exhibit organ-specific temporal signatures. Nature 583:596-602.
Balwani M, Sardh E, Ventura P, Peiro PA, Rees DC, Stolzel U, Bissell DM, Bonkovsky HL, Windyga J, Anderson KE, Parker C, Silver SM, Keel SB, Wang J, Stein PE, Harper P, Vasiliou D, Wang B, Phillips J, Ivanoa A, Langendonk JG, Kauppinen R, Minder E, Horie Y, Penz C, Chen J, Liu S, Ko JJ, Sweetser MT, Garg P, Vaishnaw A, Kim JB, Simon A, Gouya L. (2020) Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Hepatic Porphyria. NEJM 382:2289-2301. PMID: 32521132
Saberi B, Naik H, Overbey JR, Erwin AL, Anderson KE, Bissell DM, Bonkovsky HL, Phillips JD, Wang B, Singal A, McGuire B, Desnick RJ, Balwani M. (2020) Hepatocellular carcinoma in acute hepatic porphyrias: results from the longitudinal study of the U.S. Porphyrias Consortium. Hepatology 2020 Jul 18. Doi: 10.1002/hep.31460. PMID: 32681675
Alkhani, A, Levy CS, Tsui M, Polovina K, Mattis AN, Mack M, Wang B, Maher JJ, Nijagal A. (2020) Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation. Sci Rep 10:7165. PMID: 32346042
Xu M, Wang H, Wang JX, Burhan D, Shang R, Wang P, Zhou Y, Li R, Liang BY, Evert K, Utpatel K, Xu Z, Xong XH, Che L, Calvisi, DF, Wang B, Chen X, Zeng Y, Chen X. (2020) mTorc2 signaling is necessary for timely liver regeneration after partial hepatectomy. American Journal of Pathology 190:817-829. PMID: 32035060
2019:
Qiao Y, Wang J, Karagoz E, Liang B, Song X, Shang R, Evert K, Xu M, Che L, Evert M, Calvisi DF, Tao J, Wang B, Monga SP, Chen X. (2019) Axin1 deletion induced hepatocarcinogenesis requires intact β-Catenin but not Notch cascade in mice. Hepatology 70:2003-2017. PMID: 30737831
Zhao L, Jin Y, Donahue K, Tsui M, Fish M, Logan CY, Wang B*, Nusse R*. (2019) Tissue repair in the mouse liver following acute carbon tetrachloride toxicity depends on injury-induced Wnt/beta-catenin signaling. Hepatology Epub 2019 Feb 14. Doi: 10.1002/hep.30563. PMID: 30762896 (PDF) * Co-corresponding authors.
2018:
Peng WC, Logan CY, Fish M, Anbarchian T, Aguisanda F, Alvarez A, Wu P, Jin Y, Zhu J, Li B, Grompe M, Wang B, Nusse R. (2018) Tissue repair signals and in vitro culture: inflammatory cytokine TNFa promotes the expansion of primary hepatocytes in 3D culture. Cell 175:1607-1619. PMID: 30500539. (PDF)
The Tabula Muris Consortium (2018) Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris. Nature 562:367-372. PMID: 30283141. (PDF)
2015 and earlier:
Wang B*, Zhao L, Fish M, Logan CY, Nusse R*. (2015) Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver. Nature 524(7564):180-185. PMCID: PMC4589224. (PDF) * Co-corresponding authors.
See: coverage in Nature: News & Views, Nature Medicine: Notable Advances 2015
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